In the experiment of Gundersen’s group on mice to simulate the muscle by working them work harder. Within a month the number of nuclei within the mice’s muscle have appear in over 50 percent. These amount of nuclei come first before the muscle mass that is provided afterward. Then the researchers would let them stop working and deflate the muscles cells for about 40 percent, yet the nuclei still remains. Nuclei stores muscle memories so that it will retain the date of how much muscle mass to built in for certain exercise. This show that athletes can come back from being inactive and the exercise will quickly retain the amount of muscles mass that have lost.
This data create a big controversy over the science peer-reviewed data about how cells are suppose to atrophy and apoptosis will be happening. Previous data is being contradicted, because Gundersen’s data found out that during the apoptosis if inactive the cells that are dying were not muscle fibers or nuclei. Muscle physiologist Bengt Saltin and cell biologist Lawrence Schwartz have approved the Gundersen’s data.
If the result is publish in truth, sport agencies may want to consider the time to ban athletes for taking steroids. Also the fact that these nuclei is long lasting show that it is a good idea to get involve in exercise when you’re young so that retaining muscles when you’re elder would be easier as when people age their ability to build muscle mass decline.
http://www.usnews.com/science/articles/2010/08/18/muscles-remember-past-glory.html
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